Cannabidiol attenuates methamphetamine-induced conditioned place preference via the Sigma1R/AKT/GSK-3β/CREB signaling pathway in rats

Methamphetamine (METH) is a highly addictive psychostimulant. Cannabidiol (CBD) is an exogenous cannabinoid without psychostimulating activity, which has potential therapeutic effects on opioid addiction. However, it is unclear whether CBD has therapeutic effects on METH-induced motivational effects...

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Veröffentlicht in:Toxicol Res (Camb)
Hauptverfasser: Yang, Genmeng, Liu, Liu, Zhang, Ruilin, Li, Juan, Leung, Chi-Kwan, Huang, Jian, Li, Yuanyuan, Shen, Baoyu, Zeng, Xiaofeng, Zhang, Dongxian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329178/
https://ncbi.nlm.nih.gov/pubmed/32670551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfaa021
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