Phase 1 clinical study of cell therapy with effective-mononuclear cells (E-MNC) for radiogenic xerostomia (first-in-human study) (FIH study on E-MNC therapy for radiogenic xerostomia)

BACKGROUND: Treatment for most patients with head and neck cancers includes ionizing radiation with or without chemotherapy. This treatment causes irreversible damage to salivary glands in the irradiation field accompanied by a loss of fluid-secreting acinar cells and a considerable decrease of sali...

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Publicado en:Medicine (Baltimore)
Autores principales: Sumita, Yoshinori, Iwamoto, Naoki, Seki, Makoto, Yoshida, Takako, Honma, Ryo, Iwatake, Mayumi, Ohba, Seigo, Takashi, I., Hotokezaka, Yuka, Harada, Hiroshi, Kuroshima, Shinichiro, Nagai, Kazuhiro, Asahara, Takayuki, Atsushi Kawakam, I, Asahina, Izumi
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Health 2020
Materias:
3700
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328916/
https://ncbi.nlm.nih.gov/pubmed/32590759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000020788
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