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Zebrafish models of skeletal dysplasia induced by cholesterol biosynthesis deficiency
Human disorders of the post-squalene cholesterol biosynthesis pathway frequently result in skeletal abnormalities, yet our understanding of the mechanisms involved is limited. In a forward-genetic approach, we have found that a late-onset skeletal mutant, named koliber(nu7), is the result of a cis-a...
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| Pubblicato in: | Dis Model Mech |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7328163/ https://ncbi.nlm.nih.gov/pubmed/32430393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042549 |
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