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The lncRNA Gm15622 stimulates SREBP-1c expression and hepatic lipid accumulation by sponging the miR-742-3p in mice

Excessive lipid deposition is a hallmark of NAFLD. Although much has been learned about the enzymes and metabolites involved in NAFLD, few studies have focused on the role of long noncoding RNAs (lncRNAs) in hepatic lipid accumulation. Here, using in vitro and in vivo models of NAFLD, we found that...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Ma, Minjuan, Duan, Rui, Shen, Lulu, Liu, Mengting, Ji, Yaya, Zhou, Hao, Li, Changxian, Liang, Tingming, Li, Xiangcheng, Guo, Li
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328049/
https://ncbi.nlm.nih.gov/pubmed/32229588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000664
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