Parenteral lipids shape gut bile acid pools and microbiota profiles in the prevention of cholestasis in preterm pigs

Multi-component lipid emulsions, rather than soy-oil emulsions, prevent cholestasis by an unknown mechanism. Here, we quantified liver function, bile acid pools, and gut microbial and metabolite profiles in premature parenterally fed pigs given a soy-oil lipid emulsion, Intralipid (IL), a multi comp...

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Pubblicato in:J Lipid Res
Autori principali: Call, Lee, Molina, Tiffany, Stoll, Barbara, Guthrie, Greg, Chacko, Shaji, Plat, Jogchum, Robinson, Jason, Lin, Sen, Vonderohe, Caitlin, Mohammad, Mahmoud, Kunichoff, Dennis, Cruz, Stephanie, Lau, Patricio, Premkumar, Muralidhar, Nielsen, Jon, Fang, Zhengfeng, Olutoye, Oluyinka, Thymann, Thomas, Britton, Robert, Sangild, Per, Burrin, Douglas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328048/
https://ncbi.nlm.nih.gov/pubmed/32350078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000652
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