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Targeted cell ablation in zebrafish using optogenetic transcriptional control

Cell ablation is a powerful method for elucidating the contributions of individual cell populations to embryonic development and tissue regeneration. Targeted cell loss in whole organisms has been typically achieved through expression of a cytotoxic or prodrug-activating gene product in the cell typ...

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Bibliographic Details
Published in:Development
Main Authors: Mruk, Karen, Ciepla, Paulina, Piza, Patrick A., Alnaqib, Mohammad A., Chen, James K.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328002/
https://ncbi.nlm.nih.gov/pubmed/32414936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.183640
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