Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function

BACKGROUND: Ischemic stroke can induce changes in mitochondrial morphology and function. As a regulatory gene in mitochondria, optic atrophy 1 (OPA1) plays a pivotal role in the regulation of mitochondrial dynamics and other related functions. However, its roles in cerebral ischemia-related conditio...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lai, Yongxing, Lin, Peiqiang, Chen, Manli, Zhang, Yixian, Chen, Jianhao, Zheng, Mouwei, Liu, Ji, Du, Houwei, Chen, Ronghua, Pan, Xiaodong, Liu, Nan, Chen, Hongbin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Articles from the Special Issue on Redox Signalling and Cardiovascular Disease; Edited by Christopher Kevil and Yabing Chen
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327985/
https://ncbi.nlm.nih.gov/pubmed/32199783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101503
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