The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) 1A1 and CYP1A2, which are important enzymes in metabolism of xenobiotics. The AHR is activated upon binding of polycyclic...

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Опубликовано в: :Redox Biol
Главные авторы: Vogel, Christoph F.A., Van Winkle, Laura S., Esser, Charlotte, Haarmann-Stemmann, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
Предметы:
Articles from the Special Issue on Impact of environmental pollution and stress on redox signaling and oxidative stress pathways; Edited by Thomas Münzel and Andreas Daiber
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327980/
https://ncbi.nlm.nih.gov/pubmed/32354640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101530
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