Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release

This study aimed to prepare poly (D, L-lactic-co-glycolic acid) microspheres (PLGA-Ms) by a modified solid-in-oil-in-water (S/O/W) multi-emulsion technique in order to achieve sustained release with reduced initial burst and maintain efficient drug concentration for a prolonged period of time. Compo...

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Udgivet i:Asian J Pharm Sci
Main Authors: Dong, Ni, Zhu, Chune, Jiang, Junhuang, Huang, Di, Li, Xing, Quan, Guilan, Liu, Yang, Tan, Wen, Pan, Xin, Wu, Chuanbin
Format: Artigo
Sprog:Inglês
Udgivet: Shenyang Pharmaceutical University 2020
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327764/
https://ncbi.nlm.nih.gov/pubmed/32636952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2019.01.002
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