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A realistic appraisal of the use of embryonic stem cell-based therapies for cardiac repair

Despite the well-documented capacity of embryonic stem cells (ESCs) to differentiate into cardiomyocytes, transplantation of ESCs or ESC-derived cells is plagued by several formidable problems, including graft rejection, arrhythmias, and potential risk of teratomas. Life-long immunosuppression is a...

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Bibliografiske detaljer
Udgivet i:Eur Heart J
Main Authors: Wysoczynski, Marcin, Bolli, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327535/
https://ncbi.nlm.nih.gov/pubmed/31778154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz787
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