An Autonomous Oscillation Times and Executes Centriole Biogenesis

The accurate timing and execution of organelle biogenesis is crucial for cell physiology. Centriole biogenesis is regulated by Polo-like kinase 4 (Plk4) and initiates in S-phase when a daughter centriole grows from the side of a pre-existing mother. Here, we show that a Plk4 oscillation at the base...

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Udgivet i:Cell
Main Authors: Aydogan, Mustafa G., Steinacker, Thomas L., Mofatteh, Mohammad, Wilmott, Zachary M., Zhou, Felix Y., Gartenmann, Lisa, Wainman, Alan, Saurya, Saroj, Novak, Zsofia A., Wong, Siu-Shing, Goriely, Alain, Boemo, Michael A., Raff, Jordan W.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327525/
https://ncbi.nlm.nih.gov/pubmed/32531200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.05.018
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