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Prolonged treatment with the synthetic glucocorticoid methylprednisolone affects adrenal steroidogenic function and response to inflammatory stress in the rat

Synthetic glucocorticoids are widely prescribed for the treatment of numerous inflammatory and autoimmune diseases and they can also affect the way the adrenal gland produces endogenous glucocorticoids. Indeed, patients undergoing synthetic glucocorticoid treatment can develop adrenal insufficiency,...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Spiga, Francesca, Zhao, Zidong, Lightman, Stafford L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327516/
https://ncbi.nlm.nih.gov/pubmed/32156515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.03.001
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