MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells

Irreversible blindness from glaucoma and optic neuropathies is attributed to retinal ganglion cells (RGCs) losing the ability to regenerate axons. While several transcription factors and proteins have demonstrated enhancement of axon regeneration after optic nerve injury, mechanisms contributing to...

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Publicado no:Mol Ther Nucleic Acids
Main Authors: Mak, Heather K., Yung, Jasmine S.Y., Weinreb, Robert N., Ng, Shuk Han, Cao, Xu, Ho, Tracy Y.C., Ng, Tsz Kin, Chu, Wai Kit, Yung, Wing Ho, Choy, Kwong Wai, Wang, Chi Chiu, Lee, Tin Lap, Leung, Christopher Kai-shun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327411/
https://ncbi.nlm.nih.gov/pubmed/32599451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.05.031
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