Nanoformulation of the superoxide dismutase mimic, MnTnBuOE-2-PyP(5+), prevents its acute hypotensive response

Scavenging superoxide (O(2)(•-)) via overexpression of superoxide dismutase (SOD) or administration of SOD mimics improves outcomes in multiple experimental models of human disease including cardiovascular disease, neurodegeneration, and cancer. While few SOD mimics have transitioned to clinical tri...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Schlichte, Sarah L., Romanova, Svetlana, Katsurada, Kenichi, Kosmacek, Elizabeth A., Bronich, Tatiana K., Patel, Kaushik P., Oberley-Deegan, Rebecca E., Zimmerman, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327277/
https://ncbi.nlm.nih.gov/pubmed/32863236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101610
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