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Temporal Control of the Helicobacter pylori Cag Type IV Secretion System in a Mongolian Gerbil Model of Gastric Carcinogenesis

The Helicobacter pylori Cag type IV secretion system (T4SS) translocates the effector protein CagA and nonprotein bacterial constituents into host cells. In this study, we infected Mongolian gerbils with an H. pylori strain in which expression of the cagUT operon (required for Cag T4SS activity) is...

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Veröffentlicht in:mBio
Hauptverfasser: Lin, Aung Soe, McClain, Mark S., Beckett, Amber C., Caston, Rhonda R., Harvey, M. Lorena, Dixon, Beverly R. E. A., Campbell, Anne M., Shuman, Jennifer H. B., Sawhney, Neha, Delgado, Alberto G., Loh, John T., Piazuelo, M. Blanca, Algood, Holly M. Scott, Cover, Timothy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327173/
https://ncbi.nlm.nih.gov/pubmed/32605987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01296-20
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