Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a newly emerging viral disease with fatal outcomes. However, no MERS-CoV-specific treatment is commercially available. Given the absence of previous structure-based drug discovery studies targeting MERS-CoV fusion proteins, this set of compo...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Kandeel, Mahmoud, Yamamoto, Mizuki, Al-Taher, Abdulla, Watanabe, Aya, Oh-hashi, Kentaro, Park, Byoung Kwon, Kwon, Hyung-Joo, Inoue, Jun-ichiro, Al-Nazawi, Mohammed
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327142/
https://ncbi.nlm.nih.gov/pubmed/32126736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2019.202
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