Centrosome dysfunction: a link between senescence and tumor immunity

Centrosome aberrations are hallmarks of human cancers and contribute to the senescence process. Structural and numerical centrosome abnormalities trigger mitotic errors, cellular senescence, cell death, genomic instability and/or aneuploidy, resulting in human disorders such as aging and cancer and...

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Bibliographic Details
Published in:Signal Transduct Target Ther
Main Authors: Wu, Qi, Li, Bei, Liu, Le, Sun, Shengrong, Sun, Si
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327052/
https://ncbi.nlm.nih.gov/pubmed/32606370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00214-7
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