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Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

Pain medication plays an important role in the treatment of acute and chronic pain conditions, but some drugs, opioids in particular, have been overprescribed or prescribed without adequate safeguards, leading to an alarming rise in medication-related overdose deaths. The NIH Helping to End Addictio...

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Vydáno v:Nat Rev Neurol
Hlavní autoři: Davis, Karen D., Aghaeepour, Nima, Ahn, Andrew H., Angst, Martin S., Borsook, David, Brenton, Ashley, Burczynski, Michael E., Crean, Christopher, Edwards, Robert, Gaudilliere, Brice, Hergenroeder, Georgene W., Iadarola, Michael J., Iyengar, Smriti, Jiang, Yunyun, Kong, Jiang-Ti, Mackey, Sean, Saab, Carl Y., Sang, Christine N., Scholz, Joachim, Segerdahl, Marta, Tracey, Irene, Veasley, Christin, Wang, Jing, Wager, Tor D., Wasan, Ajay D., Pelleymounter, Mary Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326705/
https://ncbi.nlm.nih.gov/pubmed/32541893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41582-020-0362-2
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