Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development

VGCCs are multisubunit complexes that play a crucial role in neuronal signaling. Auxiliary α2δ subunits of VGCCs modulate trafficking and biophysical properties of the pore-forming α1 subunit and trigger excitatory synaptogenesis. Alterations in the expression level of α2δ subunits were implicated i...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Bikbaev, Arthur, Ciuraszkiewicz-Wojciech, Anna, Heck, Jennifer, Klatt, Oliver, Freund, Romy, Mitlöhner, Jessica, Enrile Lacalle, Sara, Sun, Miao, Repetto, Daniele, Frischknecht, Renato, Ablinger, Cornelia, Rohlmann, Astrid, Missler, Markus, Obermair, Gerald J., Di Biase, Valentina, Heine, Martin
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2020
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326358/
https://ncbi.nlm.nih.gov/pubmed/32414783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1707-19.2020
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