Partial MHC/neuroantigen peptide constructs attenuate methamphetamine-seeking and brain chemokine (C-C motif) ligand 2 levels in rats

There are no medications that target the neurotoxic effects or reduce the use of methamphetamine. Recombinant T-cell receptor ligand (RTL) 1000 [a partial major histocompatibility complex (pMHC) class II construct with a tethered myelin peptide], addresses the neuroimmune effects of methamphetamine...

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Publicat a:Eur J Pharmacol
Autors principals: Loftis, Jennifer M., Navis, Tommy, Taylor, Jonathan, Hudson, Rebekah, Person, Ulziibat, Lattal, K. Matthew, Vandenbark, Arthur A., Shirley, Renee, Huckans, Marilyn
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326336/
https://ncbi.nlm.nih.gov/pubmed/32416183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173175
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