Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass

Osteoporosis is a genetic disease characterized by progressive reductions in bone mineral density (BMD) leading to an increased risk of fracture. Over the last decade, genome-wide association studies (GWASs) have identified over 1000 associations for BMD. However, as a phenotype BMD is challenging a...

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Pubblicato in:PLoS Genet
Autori principali: Doolittle, Madison L., Calabrese, Gina M., Mesner, Larry D., Godfrey, Dana A., Maynard, Robert D., Ackert-Bicknell, Cheryl L., Farber, Charles R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326283/
https://ncbi.nlm.nih.gov/pubmed/32497039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008805
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