Utilising animal models to evaluate oseltamivir efficacy against influenza A and B viruses with reduced in vitro susceptibility

The neuraminidase (NA) inhibitor (NAI) oseltamivir (OST) is the most widely used influenza antiviral drug. Several NA amino acid substitutions are reported to reduce viral susceptibility to OST in in vitro assays. However, whether there is a correlation between the level of reduction in susceptibili...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Farrukee, Rubaiyea, Tai, Celeste Ming-Kay, Oh, Ding Yuan, Anderson, Danielle E., Gunalan, Vithiagaran, Hibberd, Martin, Lau, Gary Yuk-Fai, Barr, Ian G., von Messling, Veronika, Maurer-Stroh, Sebastian, Hurt, Aeron C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326275/
https://ncbi.nlm.nih.gov/pubmed/32555740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008592
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