In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System

Tendons and ligaments are pivotal connective tissues that tightly connect muscle and bone. In this study, we developed a novel approach to generate tendon/ligament-like tissues with a hierarchical structure, by introducing the tendon/ligament-specific transcription factor Mohawk (MKX) into the mesen...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Kataoka, Kensuke, Kurimoto, Ryota, Tsutsumi, Hiroki, Chiba, Tomoki, Kato, Tomomi, Shishido, Kana, Kato, Mariko, Ito, Yoshiaki, Cho, Yuichiro, Hoshi, Osamu, Mimata, Ayako, Sakamaki, Yuriko, Nakamichi, Ryo, Lotz, Martin K., Naruse, Keiji, Asahara, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326056/
https://ncbi.nlm.nih.gov/pubmed/32671057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00307
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