A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection

In many infectious diseases, the immune response operates as a double-edged sword. While required for protective immunity, infection-induced inflammation can be detrimental if it is not properly controlled, causing collateral body damage and potentially leading to death. It is in this context that t...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: De Trez, Carl, Stijlemans, Benoit, Bockstal, Viki, Cnops, Jennifer, Korf, Hannelie, Van Snick, Jacques, Caljon, Guy, Muraille, Eric, Humphreys, Ian R., Boon, Louis, Van Ginderachter, Jo A., Magez, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325990/
https://ncbi.nlm.nih.gov/pubmed/32655552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01085
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