Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis

BACKGROUND: More effective and safer treatments are needed for antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. METHODS: We conducted a randomized trial with a 2-by-2 factorial design to evaluate the use of plasma exchange and two regimens of oral glucocorticoids in patients with se...

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Publicado no:N Engl J Med
Main Authors: Walsh, Michael, Merkel, Peter A., Peh, Chen-Au, Szpirt, Wladimir M., Puéchal, Xavier, Fujimoto, Shouichi, Hawley, Carmel M., Khalidi, Nader, Floßmann, Oliver, Wald, Ron, Girard, Louis P., Levin, Adeera, Gregorini, Gina, Harper, Lorraine, Clark, William F., Pagnoux, Christian, Specks, Ulrich, Smyth, Lucy, Tesar, Vladimir, Ito-Ihara, Toshiko, de Zoysa, Janak Rashme, Szczeklik, Wojciech, Flores-Suárez, Luis Felipe, Carette, Simon, Guillevin, Loïc, Pusey, Charles D., Casian, Alina L., Brezina, Biljana, Mazzetti, Andrea, McAlear, Carol A., Broadhurst, Elizabeth, Reidlinger, Donna, Mehta, Samir, Ives, Natalie, Jayne, David R.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325726/
https://ncbi.nlm.nih.gov/pubmed/32053298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1803537
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