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Mitochondrial–nuclear heme trafficking in budding yeast is regulated by GTPases that control mitochondrial dynamics and ER contact sites

Heme is a cofactor and signaling molecule that is essential for much of aerobic life. All heme-dependent processes in eukaryotes require that heme is trafficked from its site of synthesis in the mitochondria to hemoproteins located throughout the cell. However, the mechanisms governing the mobilizat...

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Библиографические подробности
Опубликовано в: :J Cell Sci
Главные авторы: Martinez-Guzman, Osiris, Willoughby, Mathilda M., Saini, Arushi, Dietz, Jonathan V., Bohovych, Iryna, Medlock, Amy E., Khalimonchuk, Oleh, Reddi, Amit R.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325432/
https://ncbi.nlm.nih.gov/pubmed/32265272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.237917
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