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Association of Statin and Its Lipophilicity With Cardiovascular Events in Patients Receiving Chronic Dialysis

Lipophilicity of statins has been linked to extrahepatic cell penetration and inhibition of isoprenoid synthesis and coenzyme Q10, which may affect myocardial contraction. Whether statins' lipophilicity affects the risk of cardiovascular disease development in patients under dialysis is unclear...

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Publicat a:Clin Pharmacol Ther
Autors principals: Wang, Shih‐Wei, Li, Lung‐Chih, Su, Chien‐Hao, Yang, Yao‐Hsu, Hsu, Tsuen‐Wei, Hsu, Chien‐Ning
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325317/
https://ncbi.nlm.nih.gov/pubmed/31715017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1722
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