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Peripheral nerve injury reduces the excitation-inhibition balance of basolateral amygdala inputs to prelimbic pyramidal neurons projecting to the periaqueductal gray

Cellular and synaptic mechanisms underlying how chronic pain induces maladaptive alterations to local circuits in the medial prefrontal cortex (mPFC), while emerging, remain unresolved. Consistent evidence shows that chronic pain attenuates activity in the prelimbic (PL) cortex, a mPFC subregion. Th...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Cheriyan, John, Sheets, Patrick L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325111/
https://ncbi.nlm.nih.gov/pubmed/32600466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00638-w
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