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Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs

Naïve human pluripotent stem cells (hPSC) resemble the embryonic epiblast at an earlier time-point in development than conventional, ‘primed’ hPSC. We present a comprehensive miRNA profiling of naïve-to-primed transition in hPSC, a process recapitulating aspects of early in vivo embryogenesis. We id...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Dodsworth, Benjamin T., Hatje, Klas, Rostovskaya, Maria, Flynn, Rowan, Meyer, Claas A., Cowley, Sally A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324611/
https://ncbi.nlm.nih.gov/pubmed/32601281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67376-w
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