Differential expression of polyamine biosynthetic pathways in skin lesions and in plasma reveals distinct profiles in diffuse cutaneous leishmaniasis

Tegumentary leishmaniasis (TL) is a parasitic disease that can result in wide spectrum clinical manifestations. It is necessary to understand host and parasite determinants of clinical outcomes to identify novel therapeutic targets. Previous studies have indicated that the polyamine biosynthetic pat...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Malta-Santos, Hayna, França-Costa, Jaqueline, Macedo, Amanda, Queiroz, Artur T. L., Fukutani, Kiyoshi F., Muxel, Sandra Marcia, Khouri, Ricardo, Van Weyenbergh, Johan, Boaventura, Viviane, Barral, Aldina, Costa, Jackson M., Floh, Eny Iochevet Segal, Andrade, Bruno B., Floeter-Winter, Lucile M., Borges, Valéria M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324605/
https://ncbi.nlm.nih.gov/pubmed/32601369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67432-5
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