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Rapid and sensitive large-scale screening of low affinity extracellular receptor protein interactions by using reaction induced inhibition of Gaussia luciferase

Extracellular protein interactions mediated by cell surface receptors are essential for intercellular communication in multicellular organisms. Assays to detect extracellular interactions must account for their often weak binding affinities and also the biochemical challenges in solubilising membran...

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Publicat a:Sci Rep
Autors principals: Galaway, Francis, Wright, Gavin J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324543/
https://ncbi.nlm.nih.gov/pubmed/32601498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67468-7
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