Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome

Hypoplastic left heart syndrome (HLHS) is a clinically and anatomically severe form of congenital heart disease; however, its etiology remains largely unknown. We previously demonstrated that genetic variants in the MYH6 gene are significantly associated with HLHS. Additionally, induced pluripotent...

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Publicado en:Front Cell Dev Biol
Autores principales: Kim, Min-Su, Fleres, Brandon, Lovett, Jerrell, Anfinson, Melissa, Samudrala, Sai Suma K., Kelly, Lauren J., Teigen, Laura E., Cavanaugh, Matthew, Marquez, Maribel, Geurts, Aron M., Lough, John W., Mitchell, Michael E., Fitts, Robert H., Tomita-Mitchell, Aoy
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324479/
https://ncbi.nlm.nih.gov/pubmed/32656206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00440
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