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Quantifying molecular bias in DNA data storage

DNA has recently emerged as an attractive medium for archival data storage. Recent work has demonstrated proof-of-principle prototype systems; however, very uneven (biased) sequencing coverage has been reported, which indicates inefficiencies in the storage process. Deviations from the average cover...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chen, Yuan-Jyue, Takahashi, Christopher N., Organick, Lee, Bee, Callista, Ang, Siena Dumas, Weiss, Patrick, Peck, Bill, Seelig, Georg, Ceze, Luis, Strauss, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324401/
https://ncbi.nlm.nih.gov/pubmed/32601272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16958-3
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