Free fatty acid processing diverges in human pathologic insulin resistance conditions

BACKGROUND: Postreceptor insulin resistance (IR) is associated with hyperglycemia and hepatic steatosis. However, receptor-level IR (e.g., insulin receptor pathogenic variants, INSR) causes hyperglycemia without steatosis. We examined 4 pathologic conditions of IR in humans to examine pathways contr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Sekizkardes, Hilal, Chung, Stephanie Therese, Chacko, Shaji, Haymond, Morey W., Startzell, Megan, Walter, Mary, Walter, Peter J., Lightbourne, Marissa, Brown, Rebecca J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Clinical Medicine
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324196/
https://ncbi.nlm.nih.gov/pubmed/32191645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135431
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