Proinflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice

Ischemic acute kidney injury (AKI), a complication that frequently occurs in hospital settings, is often associated with hemodynamic compromise, sepsis, cardiac surgery, or exposure to nephrotoxins. Here, using a murine renal ischemia/reperfusion injury (IRI) model, we show that intercalated cells (...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Battistone, Maria Agustina, Mendelsohn, Alexandra C., Spallanzani, Raul German, Allegretti, Andrew S., Liberman, Rachel N., Sesma, Juliana, Kalim, Sahir, Wall, Susan M., Bonventre, Joseph V., Lazarowski, Eduardo R., Brown, Dennis, Breton, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324186/
https://ncbi.nlm.nih.gov/pubmed/32287042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134791
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