The role of ADAM proteolysis and mechanical damage in non-physiological shear stress induced platelet receptor shedding

In order to explore the role of a disintegrin and metalloproteinase (ADAM) proteolysis and direct mechanical damage in non-physiological shear stress (NPSS)-caused platelet receptor shedding, the healthy donor blood treated with/without ADAM inhibitor was exposed to NPSS (150 Pa). The expression of...

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Foilsithe in:ASAIO J
Main Authors: Chen, Zengsheng, Tran, Douglas, Li, Tieluo, Arias, Katherin, Griffith, Bartley P., Wu, Zhongjun J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323905/
https://ncbi.nlm.nih.gov/pubmed/31192844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAT.0000000000001028
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