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Initial joint bleed volume in a delayed on‐demand treatment setup correlates with subsequent synovial changes in hemophilic mice

BACKGROUND: Hemophilic arthropathy is a debilitating morbidity of hemophilia caused by recurrent joint bleeds. We investigated if the joint bleed volume, before initiation of treatment, was linked to the subsequent degree of histopathological changes and the development of bone pathology in a mouse...

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Detalhes bibliográficos
Publicado no:Animal Model Exp Med
Main Authors: Vøls, Kåre Kryger, Kjelgaard‐Hansen, Mads, Ley, Carsten Dan, Hansen, Axel Kornerup, Petersen, Maj
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323705/
https://ncbi.nlm.nih.gov/pubmed/32613175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ame2.12118
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