Phenotype instability of hepatocyte-like cells produced by direct reprogramming of mesenchymal stromal cells

BACKGROUND: Hepatocyte-like cells (iHEPs) generated by transcription factor-mediated direct reprogramming of somatic cells have been studied as potential cell sources for the development of novel therapies targeting liver diseases. The mechanisms involved in direct reprogramming, stability after lon...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Orge, Iasmim Diniz, Gadd, Victoria L., Barouh, Judah Leão, Rossi, Erik Aranha, Carvalho, Rejane Hughes, Smith, Ian, Allahdadi, Kyan James, Paredes, Bruno Diaz, Silva, Daniela Nascimento, Damasceno, Patrícia Kauanna F., Sampaio, Gabriela Louise, Forbes, Stuart J., Soares, Milena Botelho Pereira, Souza, Bruno Solano de Freitas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323614/
https://ncbi.nlm.nih.gov/pubmed/32276654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01665-z
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