Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock

BACKGROUND: Platelets have been demonstrated to be potent activators of neutrophil extracellular trap (NET) formation during sepsis. However, the mediators and molecular pathways involved in human platelet-mediated NET generation remain poorly defined. Circulating plasma exosomes mostly originating...

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Bibliographische Detailangaben
Veröffentlicht in:Crit Care
Hauptverfasser: Jiao, Yang, Li, Weiwei, Wang, Wei, Tong, Xingyu, Xia, Ran, Fan, Jie, Du, Jianer, Zhang, Chengmi, Shi, Xueyin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322900/
https://ncbi.nlm.nih.gov/pubmed/32600436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03082-3
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