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PRKCQ inhibition enhances chemosensitivity of triple-negative breast cancer by regulating Bim
BACKGROUND: Protein kinase C theta, (PRKCQ/PKCθ) is a serine/threonine kinase that is highly expressed in a subset of triple-negative breast cancers (TNBC) and promotes their growth, anoikis resistance, epithelial-mesenchymal transition (EMT), and invasion. Here, we show that PRKCQ regulates the sen...
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| Publicado en: | Breast Cancer Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7322866/ https://ncbi.nlm.nih.gov/pubmed/32600444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01302-w |
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