Multigroup, Adaptively Randomized Trials Are Advantageous for Comparing Coronavirus Disease 2019 (COVID-19) Interventions

In this commentary, the authors explain and call for a broader use of outcome-adaptive randomization when designing clinical trials to test multiple COVID-19 interventions. This design potentially reduces the number of deaths or other adverse outcomes incurred during a trial.

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Detalhes bibliográficos
Publicado no:Ann Intern Med
Main Authors: Magaret, Amalia S., Jacob, Shevin T., Halloran, M. Elizabeth, Guthrie, Katherine A., Magaret, Craig A., Johnston, Christine, Simon, Noah R., Wald, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Physicians 2020
Assuntos:
Ideas and Opinions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322770/
https://ncbi.nlm.nih.gov/pubmed/32525715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/M20-2933
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