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Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails

We have previously introduced the use of permeabilized fission yeast cells (enzyme bags) that recombinantly express full-length CYPs for drug metabolism studies. Such enzyme bags are cells with pores that function as enzymes in situ. They can easily be prepared without a need for ultracentrifugation...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Sharma, Sangeeta Shrestha, Sharma, Shishir, Bureik, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322738/
https://ncbi.nlm.nih.gov/pubmed/32612874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2020.05.003
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