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Rho-Mediated Activation of PI(4)P5K and Lipid Second Messengers is Necessary for Promotion of Angiogenesis by Semaphorin 4D
Phosphatidylinositol 4-phosphate 5-kinase (PI(4)P5K) is a type I lipid kinase that generates the lipid second messenger phospholipid phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and functions downstream of RhoA in actin organization. It is known to play an essential role in neurite remodeling,...
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| Veröffentlicht in: | Angiogenesis |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7322696/ https://ncbi.nlm.nih.gov/pubmed/21538148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-011-9214-4 |
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