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Transcriptome changes during the initiation and progression of Duchenne muscular dystrophy in Caenorhabditis elegans

Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease characterized by progressive muscle degeneration. The condition is driven by nonsense and missense mutations in the dystrophin gene, leading to instability of the sarcolemma and skeletal muscle necrosis and atrophy. Resulting changes in...

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發表在:Hum Mol Genet
Main Authors: Hrach, Heather C, O’Brien, Shannon, Steber, Hannah S, Newbern, Jason, Rawls, Alan, Mangone, Marco
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322572/
https://ncbi.nlm.nih.gov/pubmed/32227114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa055
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