Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2

BACKGROUND: Identifying effective drugs to suppress vascular inflammation is a promising strategy to delay the progression of abdominal aortic aneurysm (AAA). Itaconate has a vital role in regulating inflammatory activation in various inflammatory diseases. However, the role of itaconate in the prog...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Song, Haoyu, Xu, Tong, Feng, Xiaofei, Lai, Yanxian, Yang, Yang, Zheng, Hao, He, Xiang, Wei, Guoquan, Liao, Wangjun, Liao, Yulin, Zhong, Lintao, Bin, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322255/
https://ncbi.nlm.nih.gov/pubmed/32574955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102832
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