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The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation

During infection, the bacterial pathogen Legionella pneumophila manipulates a variety of host cell signaling pathways, including the Hippo pathway which controls cell proliferation and differentiation in eukaryotes. Our previous studies revealed that L. pneumophila encodes the effector kinase LegK7...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Lee, Pei-Chung, Beyrakhova, Ksenia, Xu, Caishuang, Boniecki, Michal T., Lee, Mitchell H., Onu, Chisom J., Grishin, Andrey M., Machner, Matthias P., Cygler, Miroslaw
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322029/
https://ncbi.nlm.nih.gov/pubmed/32513747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000497117
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