Spatial confinement of receptor activity by tyrosine phosphatase during directional cell migration

Directional cell migration involves signaling cascades that stimulate actin assembly at the leading edge, and additional pathways must inhibit actin polymerization at the rear. During neuroblast migration in Caenorhabditis elegans, the transmembrane protein MIG-13/Lrp12 acts through the Arp2/3 nucle...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Zhu, Zhiwen, Chai, Yongping, Hu, Huifang, Li, Wei, Li, Wen-Jun, Dong, Meng-Qiu, Wu, Jia-Wei, Wang, Zhi-Xin, Ou, Guangshuo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321996/
https://ncbi.nlm.nih.gov/pubmed/32513699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003019117
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