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Spatial confinement of receptor activity by tyrosine phosphatase during directional cell migration

Directional cell migration involves signaling cascades that stimulate actin assembly at the leading edge, and additional pathways must inhibit actin polymerization at the rear. During neuroblast migration in Caenorhabditis elegans, the transmembrane protein MIG-13/Lrp12 acts through the Arp2/3 nucle...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhu, Zhiwen, Chai, Yongping, Hu, Huifang, Li, Wei, Li, Wen-Jun, Dong, Meng-Qiu, Wu, Jia-Wei, Wang, Zhi-Xin, Ou, Guangshuo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321996/
https://ncbi.nlm.nih.gov/pubmed/32513699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003019117
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