Early Changes in Cartilage Pericellular Matrix Micromechanobiology Portend the Onset of Post-Traumatic Osteoarthritis

The pericellular matrix (PCM) of cartilage is a structurally distinctive microdomain surrounding each chondrocyte, and is pivotal for cell homeostasis and cell-matrix interactions in healthy tissue. This study queried if the PCM is the initiation point for disease or a casualty of more widespread ma...

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Veröffentlicht in:Acta Biomater
Hauptverfasser: Chery, Daphney R., Han, Biao, Li, Qing, Zhou, Ying, Heo, Su-Jin, Kwok, Bryan, Chandrasekaran, Prashant, Wang, Chao, Qin, Ling, Lu, X. Lucas, Kong, Dehan, Enomoto-Iwamoto, Motomi, Mauck, Robert L., Han, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321882/
https://ncbi.nlm.nih.gov/pubmed/32428685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.05.005
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