LEM2 phase separation governs ESCRT-mediated nuclear envelope reformation

During cell division, remodeling of the nuclear envelope (NE) enables chromosome segregation by the mitotic spindle(1). The reformation of sealed nuclei requires Endosomal Sorting Complexes Required for Transport (ESCRTs) and LEM2, a transmembrane ESCRT adapter(2–4). Here, we show how LEM2’s ability...

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Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: von Appen, Alexander, LaJoie, Dollie, Johnson, Isabel E., Trnka, Michael J., Pick, Sarah M., Burlingame, Alma L., Ullman, Katharine S., Frost, Adam
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321842/
https://ncbi.nlm.nih.gov/pubmed/32494070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2232-x
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