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Kappa opioid receptors internalization is protective against oxygen-glucose deprivation through β-arrestin activation and Akt-mediated signaling pathway

Hypoxia induces reversible κ-opioid receptor (KOR) internalization similar to the internalization that is induced by KOR agonists. In the current study, we demonstrate that this KOR internalization is a protective mechanism via the β-arrestin specific pathway in an oxygen-glucose deprivation (OGD) m...

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Detalhes bibliográficos
Publicado no:Neurochem Int
Main Authors: Xu, Jihong, Chen, Fang, Wang, Shuyan, Akins, Nicholas S., Hossain, Md Imran, Zhou, Yi, Huang, Jinxi, Ji, Jiafu, Xi, Jin, Lin, Wenzhen, Grothusen, John, Le, Hoang V., Liu, Renyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321825/
https://ncbi.nlm.nih.gov/pubmed/32339667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2020.104748
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